N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as Janus kinase inhibitors

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专利权人:

Incyte Holdings Corporation

发明人:

Rodgers, James D.,Shepard, Stacey,Arvanitis, Argyrios G.,Wang, Haisheng,Storace, Louis,Folmer, Beverly,Shao, Lixin,Zhu, Wenyu,Glenn, Joseph P.

申请号：

AU2010249380

公开号：

AU2010249380B2

申请日:

2010.05.21

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention relates to N-(hetero)aryl-pyrrolidine derivatives of Formula (I): which are JAK inhibitors, such as selective JAK1 inhibitors, useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/