LERCHEN HANS GEORG,HAMMER STEFANIE,HARRENGA AXEL,KOPITZ CHARLOTTE CHRISTINE,NISING CARL FRIEDRICH,SOMMER ANETTE,STELTE LUDWIG BEATRIX,MAHLERT CHRISTOPH,SCHUHMACHER JOACHIM,GOLFIER SVEN,GREVEN SIMONE,B
申请号：
IN4810/DELNP/2014
公开号：
IN2014DN04810A
申请日:
2014.06.12
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present application relates to new antibody drug conjugates (ADCs) of N N dialkylauristatins directed against the target FGFR2 drug metabolites of said ADCs a method for producing said ADCs the use of said ADCs for the treatment and/or prevention of illnesses as well as the use of said ADCs for producing pharmaceuticals for the treatment and/or prevention of illnesses particularly of hyperproliferative and/or angiogenic diseases such as carcinosis. Such treatments can be carried out as monotherapy or in combination with other pharmaceuticals or additional therapeutic measures.
