MPER-liposome conjugates and uses thereof

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专利权人:

发明人:

Barton F. Haynes,Bette T. Korber,S. Munir Alam

申请号：

US15024600

公开号：

US10076567B2

申请日:

2014.09.29

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to peptides and compositions suitable for use in inducing anti-HIV-1 antibodies. The compositions comprise HIV-1 gp41 membrane proximal external region (MPER) peptide-liposome conjugates for induction of broadly reactive anti-HIV-1 antibodies. The invention also relates to methods of inducing neutralizing anti-HIV-1 antibodies using such compositions.

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