The Feinstein Institute for Medical Research;Duke University;The Government of The United States of America as represented by The Secretary, Department of Health and Human Services
发明人:
Haynes, Barton F.,Tomaras, Georgia,Shen, Shaunna,Dimitrov, Dimiter S.,Zhu, Zhongyu,Hwang, Kwan-Ki,Chiorazzi, Nicholas
申请号:
AU2010296058
公开号:
AU2010296058A1
申请日:
2010.09.16
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates, in general, to HIV-1 specific antibodies and, in particular, to broadly neutralizing HIV-1 specific antibodies that target the gp41 membrane-proximal external region (MPER). The present invention also relates to a cell culture system, more specifically, to a method of rendering chronic lymphocytic leukemia B-cells immortal and to a method of isolating anti-viral antibodies from clones of such cells.