DO STEVEN,GOLDSMITH RICHARD,HEFFRON TIM,KOLESNIKOV ALEKSANDR,STABEN STEVEN,OLIVERO ALAN G,SIU MICHAEL,SUTHERLIN DANIEL P,ZHU BING YAN,GOLDSMITH PAUL,BAYLISS TRACY,FOLKES Adrian,PEGG NEIL
申请号：
IN7361/DELNP/2010
公开号：
IN2010DN07361A
申请日:
2010.10.18
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
Benzopyran and benzoxepin compounds of Formulas I and II, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formulas I and II for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
