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Use of inhibitors of Bruton's tyrosine kinase (Btk)
专利权人:
Pharmacyclics LLC
发明人:
Joseph J. Buggy,Laurence Elias,Gwen Fyfe,Eric Hedrick,David J. Loury,Tarak D. Mody
申请号:
US15659803
公开号:
US10004746B2
申请日:
2017.07.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.
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