Prestipino, Russell C.,Krishna, Gopal,Moton Jr., Allen E.,Fang, Larry Yun,Steinman, Marc,Waskin, Hetty Anne,Harris, David,Wan, Jiansheng
申请号：
AU2009236289
公开号：
AU2009236289B2
申请日:
2009.04.15
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present application provides novel compositions comprising posaconazole and a polymer wherein the composition has a glass transition temperature temperature (Tg) of less than about 110°C. The application also describes compositions comprising posaconazole and a polymer having a bulk density of greater than about 0.4 mg/mL. The application also describes compositions comprising posaconazole and a polymer which provide an exposure (AUCtf) of at least about 10,000 ng.hr/mL when administered to a patient in a fasted state. The application also describes a novel process for preparing these compositions.
