Larry Yun FANG,David HARRIS,Gopal KRISHNA,Allen E. Moton, JR.,Russell C. PRESTIPINO, SR.,Marc STEINMAN,Jiansheng WAN,Hetty Anne WASKIN
申请号：
US14551903
公开号：
US20150150990A1
申请日:
2014.11.24
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present application provides novel compositions comprising posaconazole and a polymer wherein the composition has a glass transition temperature temperature (Tg) of less than about 110° C. The application also describes compositions comprising posaconazole and a polymer having a bulk density of greater than about 0.4 mg/mL. The application also describes compositions comprising posaconazole and a polymer which provide an exposure (AUCtf) of at least about 10,000 ng·hr/mL when administered to a patient in a fasted state. The application also describes a novel process for preparing these compositions.
