HUANG XIANHAI,PETERSON SCOTT L,CLOSE JOSHUA T,MACCOSS RACHEL NICOLA,SILIPHAIVANH PHIENG,ASLANIAN ROBERT G,DONG LI,MCCORMICK KEVIN D,SHAO NING,BRUBAKER JASON,BUTCHER JOHN W,MARTINEZ MICHELLE,JUNG JOON
申请号：
ZA201308942
公开号：
ZA201308942B
申请日:
2013.11.27
申请国别(地区):
ZA
年份:
2015
代理人:
摘要：
The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.
