Robert G. Aslanian;John W. Butcher;Rachel Nicola MacCoss;Hongjun Zhang;Michelle Martinez;Phieng Siliphaivanh;Scott L. Peterson;Jason Brubaker;Joshua T. Close;Joon O. Jung;Purakkattle Joh;Xianhai Huang
发明人:
Xianhai Huang,Jason Brubaker,Scott L. Peterson,John W. Butcher,Joshua T. Close,Michelle Martinez,Rachel Nicola MacCoss,Joon O. Jung,Phieng Siliphaivanh,Hongjun Zhang,Robert G. Aslanian,Purakkattle Joh
申请号：
US14126579
公开号：
US20140128367A1
申请日:
2012.06.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.
