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ESTABLISHMENT OF CELL LINES WITH ALTERED MITOCHONDRIAL DNA COPY NUMBER
专利权人:
UNIVERSITY OF SOUTH ALABAMA
发明人:
Alexeyev Mikhail,Spadafora Domenico
申请号:
US201615338117
公开号:
US2017204395(A1)
申请日:
2016.10.28
申请国别(地区):
美国
年份:
2017
代理人:
摘要:
Reduced mitochondrial DNA copy number has been reported in numerous adverse clinical conditions, yet suitable tools for modulating mitochondrial DNA copy number have not been reported. The present disclosure generally pertains to methods for modulating mitochondrial DNA copy number in cells, cell clones obtained from such methods, and cell cultures obtained by culturing such cell clones.
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