A process of preparing a burdock composite micron essence at least includes the following. Dissolved and heated phospholipid is added to a vegetable oil extract and then stirred. After stirring, the above mixture is pour into a heated glycerol and then further stirred and a burdock extract aqueous solution is added. The aforementioned mixed solution is stirred at high speed, the emulsion-homogenized solution is subject to high-pressure homogenization, and a filtration membrane is used to filter the homogenized solution obtained to get a purple transparent burdock concentrate. The burdock concentrate is used to prepare the formulation of nano-micro emulsion which is easily absorbed by human body and thus grants improved health benefits.一種牛蒡複方微米精華液製程方法,係將溶解加熱後之磷脂加入加熱後之植物油萃取物進行攪拌,攪拌後倒入加熱後之甘油中繼續攪拌,之後再加入牛蒡萃取物水溶液,將前述混合後之溶液進行高速攪拌進行乳化均質,再將乳化均質後之溶液以高壓加以均質化,最後以過濾膜將均質化後之溶液加以過濾,即可得到紫色透明狀之牛蒡濃縮液。藉此,可使牛蒡濃縮液形成奈米化之微乳製劑,而於服用後達到易於人體吸收以及較佳之保健效果。