Hall, Amy Jennae,Desai, Anu,Konda, Veera,Babish, John G.,Tripp, Matthew L.,Bland, Jeff
申请号:
AU2012204133
公开号:
AU2012204133A1
申请日:
2012.07.12
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2012204133A120120802.pdf#####ABSTRACT insulin Sensitive Insulin Resistant e.g., Muscle, liver *>P13K rn"t-Msee 0.9, uscelivr P K 0 .9., Muscle, liverA insulin PKC - IRS,,,o MAPK GSK31acilo N GSK 3 cuv GLUT4 L A I G l cG L U 4 7Uptake M A GS NFkB-p65 SREBPic GS NFkB-p65 SREBPic Glycogen Storage +TNFa SCD1 FAS ACC olL6 + Mal-CoA Lipid Storagg, 1 p-oxidation Botanical compounds to modulate kinase activity are disclosed. The compounds and methods disclosed also inhibit expression of COX-2, inhibit synthesis o prostaglandins selectively in target cells, and inhibit inflammatory response selectively. The compositions contain at least one fraction isolated or derived from hops or Acacia.