High-cell density fed-batch fermentation process for producing recombinant protein

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专利权人:

Wyeth LLC

发明人:

Wei-Qiang Willie Sun,Earl Joseph Pursell

申请号：

US14135434

公开号：

US09279000B2

申请日:

2013.12.19

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Methods for producing proteins, for example, recombinant meningococcal 2086 proteins, using fed-batch fermentation with continuous input of an inducer after achieving a threshold parameter, and optionally continuous input of a carbon source, for example, a constant rate input, to improve protein yields, as well as high density protein compositions and compositions for use in the methods of the present invention, are provided.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/