PHARMACEUTICAL COMPOSITIONS CAPABLE OF INDUCING APOPTOSIS IN TUMOUR CELLS, USEFUL FOR DIAGNOSIS AND TREATMENT OF B-CHRONIC LYMPHOCYTIC LEUKAEMIA
- 专利权人:
- CENTRO DE INMUNOLGÍA MOLECULAR
- 发明人:
- MONTERO CASIMIRO, JOSÉ ENRIQUE,ALONSO RAMIREZ, RUBY,PEREZ RODRIGUES, ROLANDO
- 申请号：
- EP20070855984
- 公开号：
- EP2119453(B1)
- 申请日:
- 2007.12.24
- 申请国别(地区):
- 欧洲专利局
- 年份:
- 2015
- 代理人:
- 摘要：
The present invention is related to the branch of immunology and particularly with the generation of pharmaceutical compositions comprising a humanized monoclonal antibody recognizing the leukocyte differentiation antigen CD6. Accordingly with that statement, the purpose of this invention is to provide pharmaceutical compositions comprising a humanized anti-CD6 monoclonal antibody for the diagnosis and treatment of Lymphoproliferative Syndromes and particularly the B-Cell Chronic Lymphocytic Leukemia. The essence of the invention consist in the application of a humanized Monoclonal Antibody that recognizes the CD6 antigen, the generation of pharmaceutical compositions comprising that antibody being able to induce apoptosis of malignant cells from B-Cell Chronic Lymphocytic Leukemia patients, reaching a clinical and a histological antitumor efficacy. The field of application of the present invention extends to the Oncology.
- 来源网站：
- 中国工程科技知识中心
