Method for Diagnosing Cancer Expressing a Truncated HER2 Receptor Variation

• 收藏
• 分享

专利权人:

FUNDACIÓ PRIVADA INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL HEBRON;FUNDACIÓ PRIVADA INSTITUCIÓ CATALANA DE RECERCA IESTUDIS AVANCATS;FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCOLÒGICA DE VALL-HEB

发明人:

ARRIBAS LÓPEZ, JOAQUÍN,PEDERSEN, KIM,ANGELLINI, PIER-DAVIDE,PARRA PALAU, JOSEP LLUIS,LAOS, SIRLE,BASELGA TORRES, JOSÉ

申请号：

DK09772265

公开号：

DK2293819T3

申请日:

2009.06.05

申请国别(地区):

DK

年份:

2014

代理人:

摘要：

The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognizes an epitope of a HER2 receptor truncated form, said epitope being defined by a sequence included in SEQ ID NO: 2. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ ID NO: 1 in a patient sample.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/