WEGH RENE T,PIKKEMAAT JEROEN A,GRUELL HOLGER,WILLARD NICOLAAS P
申请号：
IN5338/CHENP/2007
公开号：
IN276002B
申请日:
2007.11.26
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The invention provides MRI contrast agents which provide a high sensitivity and which have an optimised body retention time. These agents enable the mapping of the local pH, temperature, oxygen concentration or other metabolites in a patient"s body by the use of Chemical Exchange Saturation Transfer (CEST). Particularly pH and temperature mapping are useful for the detection of small cancer lesions and localised inflammation respectively.
