Pharmaceutical composition comprising (E) -7- [4- (4-fluorophenyl) -6-isopropyl-2- [methyl (methylsulfonyl) amino] pyrimidin-5 -yl- (3R, 5S) -3, 5-dihydr0xyhept-6-en0ic acid

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专利权人:

Lek Pharmaceuticals d.d.

发明人:

Jaklic, Miha Tomaz,Naversnik, Klemen

申请号：

AU2006329006

公开号：

AU2006329006B2

申请日:

2006.12.18

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

A chemically stable formulation of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2- [methyl(methylsulfonyl)amino]pyrim idin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically-acceptable salt thereof for oral use, such as tablets, capsules, powders, granules has been developed using the substances which stabilize against formation of degradation products: lactone and oxidation product.

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