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SUBSTITUTED IMIDAZO-QUINOLINES AS NLRP3 MODULATORS
专利权人:
INNATE TUMOR IMMUNITY; INC.
发明人:
GLICK, Gary,GHOSH, Shomir,ROUSH, William R.,OLHAVA, Edward James,O'MALLEY, Daniel
申请号:
SG11201907451X
公开号:
SG11201907451XA
申请日:
2018.02.16
申请国别(地区):
SG
年份:
2019
代理人:
摘要:
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 23 August 2018 (23.08.2018) WIPO I PCT omit VIII °nolo HE oimIE (10) International Publication Number WO 2018/152396 Al N NR 1 R 2 ) ( R 6 N R 7 R 3 W O 20 18/ 15 2396 Al (51) International Patent Classification: CO7D 471/04 (2006.01) A61P 37/00 (2006.01) A61P 35/00 (2006.01) A61K 31/437 (2006.01) (21) International Application Number: PCT/US2018/018484 (22) International Filing Date: 16 February 2018 (16.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/460,677 17 February 2017 (17.02.2017) US 62/490,881 27 April 2017 (27.04.2017) US 62/573,991 18 October 2017 (18.10.2017) US (71) Applicant: INNATE TUMOR IMMUNITY, INC. [US/US]; Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). (72) Inventors: GLICK, Gary; c/o Innate Tumor Immunity, Inc., Route 206 & Province Line Road, Princeton, New Jer- sey 08543 (US). GHOSH, Shomir; c/o Innate Tumor Im- munity, Inc., Route 206 & Province Line Road, Princeton, New Jersey 08543 (US). ROUSH, William R.; c/o Innate Tumor Immunity, Inc., Route 206 & Province Line Road, Princeton, New Jersey 08543 (US). OLHAVA, Edward James; c/o Innate Tumor Immunity, Inc., Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). O'MALLEY, Daniel; c/o Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). (74) Agent: SUN, Jing G. et al.; Bristol-Myers Squibb Compa- ny, Route 206 & Province Line Road, Princeton, New Jer- sey 08543 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, K
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