PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE
CHEN, Ke,DEERBERG, Joerg,LIN, Dong,DUMMELDINGER, Michael,INANKUR, Bahar,KOLOTUCHIN, Sergei V.,LI, Jun,ROGERS, Amanda J.,ROSSO, Victor W.,SIMMONS, Eric M.,SOUMEILLANT, Maxime C. D.,TREITLER, Daniel S.
申请号：
SG11201908947Q
公开号：
SG11201908947QA
申请日:
2018.03.29
申请国别(地区):
SG
年份:
2019
代理人:
摘要：
DC, N H 0 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 04 October 2018 (04.10.2018) W I PO I PCT omit VIII °nolo OH mil O II (10) International Publication Number WO 2018/183649 Al (51) International Patent Classification: C07D 403/12 (2006.01) A61P 29/00 (2006.01) A61K 31/501 (2006.01) (21) International Application Number: PCT/US2018/025100 (22) International Filing Date: 29 March 2018 (29.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/478,789 30 March 2017 (30.03.2017) US (71) Applicant: BRISTOL-MYERS SQUIBB COMPANY [US/US]； Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). (72) Inventors: CHEN, Ke； 42 South Drive, East Brunswick, New Jersey 08816 (US). DEERBERG, Joerg； 11 Irongate Ct., Columbus, New Jersey 08022 (US). LIN, Dong； c/o Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). DUM- MELDINGER, Michael； c/o Bristol-Myers Squibb Com- pany, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). INANKUR, Bahar； c/o Bristol-My- ers Squibb Company, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). KOLOTUCHIN, Sergei V.； c/o Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). LI, Jun； c/o Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). ROGERS, Amanda J.； c/o Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). ROSSO, Victor W.； c/o Bris- tol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). SIMMONS, Eric M.； c/o Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, New Jersey 08543 (US). SOUMEILLANT, Maxime C. D.； c/o Bristol-My- ers Squibb Company, Route 206 and Province Line Road, P
