Settembre, Carmine,Ballabio, Andrea,Medina Sanabria, Diego Luis
申请号：
AU2012224653
公开号：
AU2012224653A1
申请日:
2012.03.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The invention refers to TFEB related molecules, as variants, mutants, truncated proteins,chimeras etc. that are constitutively localized in the nucleus of a eukaryote cell. Such molecules have a therapeutic applicability in all of disorders that need of an induction of the cell authophagic/lysosomal system, as lysosomal storage disorders, neurodegenerative diseases, hepatic diseases, muscle diseases and metabolic diseases.
