Andrea Ballabio,Carmine Settembre,Diego Luis Medina Sanabria
申请号：
US14811967
公开号：
US09193755B1
申请日:
2015.07.29
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention refers to TFEB related molecules, as variants, mutants, truncated proteins, chimeras etc. that are constitutively localized in the nucleus of a eukaryote cell. Such molecules have a therapeutic applicability in all of disorders that need of an induction of the cell authophagic/lysosomal system, as lysosomal storage disorders, neurodegenerative diseases, hepatic diseases, muscle diseases and metabolic diseases.
