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Inhibidores de la bomba de protones
专利权人:
TAKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
KAJINO, MASAHIRO,HASUOKA, ATSUSHI,TARUI, NAOKI,TAKAGI, TERUFUMI
申请号:
ES05790387
公开号:
ES2402362T3
申请日:
2005.09.30
申请国别(地区):
ES
年份:
2013
代理人:
摘要:
A compound represented by formula (II-a) ina compound represented by formula (II-a) wherein X1 is -SO2-, Y1 is -CH2-, R10 is a group where X1 is h -SO2-, Y1 is CH2-, R10 is an optionally substituted hydrocarbon group or an optionally substituted idrocarbonado group or an optionally substituted heterocyclic group, R11 is (i) heterocyclic optionally substituted, R11 is (i) a hydrogen atom, (ii) an aryl group C6 -14 a hydrogen atom, (ii) a C6-14 aryl group optionally substituted with 1 to 5 substituents sopcionalmente substituted with 1 to 5 substituents selected from (1) a dehalógeno atom, (2) cianoeleccionados of (1) an atom dehalógeno , (2) cyano, (3) amino optionally substituted with one or two, (3) amino optionally substituted with one or two C1-6 alkyl or acetyl, (4) C1-6 alkyl C1-6opcionalm alkyl or acetyl, (4 ) alkyl substituted C1-6opcionalmente 1 to 5 halogens, (5) C1ente alkoxy substituted with 1 to 5 halogens, (5) C1-6 alkoxy optionally substituted with 1 to 5 halogens, (-6 optionally substituted with 1 to 5 halogens, (6) phenoxy, (7) C1-6 alkylthio optionally sustitu6) phenoxy, (7) C1-6 alkylthio optionally substituted with 1 to 5 halogens, (8) acetyl and (9) aminocaido with 1 to 5 halogens, (8) acetyl and (9) aminocarbonyl, (iii) a 2- or 3-thienyl group opcionalmenrbonilo, (iii) a group 2- or 3-thienyl optionally substituted with 1 to 3 substituents seleccionadote substituted with 1 to 3 substituents selected from (1) C1-6 alkoxy and (2) a C1-6 alkyl group (s of (1) alkoxy C1- 6 and (2) a C1-6 alkyl group, (iv) 2--benzo 3 group or [b] thienyl optionally iv) 2- or 3-benzo [b] thienyl optionally substituted with 1 to 3 substituents selected desustituido with 1 to 3 substituents selected from (1) C1-6 alkoxy and (2) a C1-6 alkyl group, (v) (1) C1-6 alkoxy and (2) a C1-6 alkyl group, (v) a group 2- or 3-furyl group optionally substituted coun 2- or 3-furyl opcionalmen I substituted with 1 to 3 substituents selected from (1) alkoxy n 1 to 3 substituents select
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