Robert G. Aslanian;Junying Zheng;Kevin D. McCormick;Rema D. Bitar;Michael Y. Berlin;Yoon Joo Lee;Walter Won;Yeon-Hee Lim;Biju J. Purakkattle;Ying Huang
发明人:
Biju J. Purakkattle,Michael Y. Berlin,Yeon-Hee Lim,Rema D. Bitar,Kevin D. McCormick,Robert G. Aslanian,Yoon Joo Lee,Junying Zheng,Ying Huang,Walter Won
申请号：
US13378893
公开号：
US20120171126A1
申请日:
2010.06.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, or isomers of said compounds), having the general structure: Formula (I) wherein L, R1, R2, R3, R4, R5, and R6 are selected independently of each other and as defined herein. The present invention also provides compounds (and salts, solvates, esters, prodrugs, tautomers, and isomers) of Formulas (H-A), (II-A1), (II-A2), (II-A2.1), (ll-A-2.2), (ll-A-2.3), (II-A4), (H-B), (H-C), (III), (IV), (V), (VI), as described herein. Also provided are pharmaceutical compositions, methods of preparing, and methods of using such compounds in the treatment and prophylaxis of a wide range of immune, autoimmune, and inflammatory diseases and conditions.
