Robert G. Aslanian;Phillippa H. Solomon;Kevin D. McCormick;Rema Danielle Bitar;John A. Hey;Purakkattle J. Biju;Michael Y. Berlin;Yoon Joo Lee;Hongwu Yang;Yeon-Hee Lim;John C. Anthes
发明人:
John C. Anthes,Kevin D. McCormick,John A. Hey,Robert G. Aslanian,Purakkattle J. Biju,Michael Y. Berlin,Daniel M. Solomon,Hongwu Yang,Yeon-Hee Lim,Yoon Joo Lee,Rema Danielle Bitar
申请号：
US12736063
公开号：
US08524697B2
申请日:
2008.12.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, or isomers of said compounds), having the general structure:wherein L, R1, R2, R3, R4, R5, and R6 are selected independently of each other and as defined herein. The present invention also provides compounds (and salts, solvates, esters, prodrugs, tautomers, and isomers) of Formulas II, III, IV, V, and VI, as defined herein. Also provided are pharmaceutical compositions, methods of preparing, and methods of using such compounds in the treatment and prophylaxis of a wide range of immune, autoimmune, and inflammatory diseases and conditions.
