An environment friendly greening wall frame structure includes a wall frame, a support, a water tank, a pot and a water supply pipe. The support is disposed on the wall frame and includes a hollow tank. A fixation hole is defined at the top edge of the hollow tank and a water outlet hole is defined at the bottom edge of the hollow tank. A groove is disposed at the bottom of the support. A hook is disposed on the water tank to fixedly engage with the groove. A water outlet pipe is connected to the bottom of the water tank. The pot is placed in the hollow tank of the support. A water inlet hole is defined on the pot. The water supply pipe is disposed at the top of the wall frame. The design can fertilize and water from the top layers of the wall frame and the fertilizer and water can flow to the lower layers of the wall frame. It can save the cost and be used as a decoration wall and a partition wall.