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METHOD FOR PRODUCING RECOMBINANT VIRUS
专利权人:
OTSUKA PHARMACEUTICAL CO.; LTD.
发明人:
KAWASAKI, MASANORI,INAGAKI, KATSUYA,MIZUKOSHI, MASAMI
申请号:
EP11742284
公开号:
EP2535409A4
申请日:
2011.02.10
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
To provide a method for producing, at high purity, a recombinant baculovirus which exhibits intended immunogenicity and is useful for a pharmaceutical (e.g., a vaccine), a transfer vector for use in the production of the recombinant baculovirus, and a method for producing the transfer vector. The method for producing a transfer vector which includes therein a fusion gene containing at least one gene encoding a virus-particle-forming protein and a gene encoding a foreign immunogenic protein, the method including modifying the polynucleotide sequence of the gene encoding the virus-particle-forming protein so as not to alter the amino acid residues constituting a corresponding naturally occurring virus-particle-forming protein and/or modifying the polynucleotide sequence of the gene so that a portion of the amino acid residues constituting the naturally occurring virus-particle-forming protein is deleted.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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