A method for tightening the papillary dermis, reticular dermis, hypodermis, septa, muscle, ground substance and extracellular matrix through the administering of an aqueous solution of citric acid resulting in the reduction of skin tenting, skin folding, loose skin, flaccid skin, crepe skin, skin sag, skin lag, skin droop, laxity, nose droop and skin overhang such as jowl formation, neck laxity； therefore, tightening jaw line, nasal bridge, draping over the zygomatic arch, the neck and other structures of the face and body (excluding structures of the orbit).
