PROBLEM TO BE SOLVED: To provide compositions and methods for treating or imaging stenosis, stenotic lesions, occluded lumens, embolic phenomena or thrombotic disorders, and further provide compositions and methods for treating internal hemorrhage.SOLUTION: The present invention relates to an aggregate for therapeutic use comprising a plurality of nanoparticles which comprise bioactive compounds.SELECTED DRAWING: Figure 1A【課題】狭窄症、狭窄病変、閉塞管腔、塞栓事象、または血栓障害の治療またはイメージングのための組成物および方法、更に内出血の治療のための組成物および方法の提供。【解決手段】生物活性化合物を含有する複数のナノ粒子を含む治療使用のための凝集物。【選択図】図1A