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Apixaban liquid formulations
专利权人:
Bristol-Myers Squibb Holdings Ireland;PFIZER INC.
发明人:
Lum Susan,Badawy Sherif Ibrahim Farag
申请号:
NZ63076313
公开号:
NZ630763A
申请日:
2013.09.26
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Disclosed is an apixaban liquid formulation in which the stability and solubility of apixaban is improved. Also provided is a method of administering an apixaban liquid formulation. The liquid formulation may comprise apixaban, a vehicle which is water, and at least two solubilizers such as non-ionic surfactant, an ionic surfactant, a hydrophilic polymer, ethanol, a polyhydric alcohol, a polyethylene glycol, and a carbohydrate.
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中国工程科技知识中心
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