Apixaban liquid formulations

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专利权人:

Bristol-Myers Squibb Holdings Ireland;PFIZER INC.

发明人:

Lum Susan,Badawy Sherif Ibrahim Farag

申请号：

NZ63076313

公开号：

NZ630763A

申请日:

2013.09.26

申请国别(地区):

NZ

年份:

2017

代理人:

摘要：

Disclosed is an apixaban liquid formulation in which the stability and solubility of apixaban is improved. Also provided is a method of administering an apixaban liquid formulation. The liquid formulation may comprise apixaban, a vehicle which is water, and at least two solubilizers such as non-ionic surfactant, an ionic surfactant, a hydrophilic polymer, ethanol, a polyhydric alcohol, a polyethylene glycol, and a carbohydrate.

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