FORMULATION PHARMACEUTIQUE STABLE DESTINÉE À UNE ADMINISTRATION PAR VOIE ORALE COMPRENANT DE LA LÉVOCÉTIRIZINE OU UN SEL PHARMACEUTIQUEMENT ACCEPTABLE DE CELLE-CI, ET DU MONTÉLUKAST OU UN SEL PHARMACEUTIQUEMENT ACCEPTABLE DE CELUI-CI
KWON, TAEK KWAN,KIM, DONG HO,KIM, KYEONG SOO,KIM, YONG IL,PARK, JAE HYUN,WOO, JONG SOO
申请号：
EP13733789
公开号：
EP2800558A4
申请日:
2013.01.04
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The present invention relates to a pharmaceutical formulation for oral administration for preventing or treating allergic rhinitis or asthma, which comprises: (a) a first particle part comprising levocetirizine or a pharmaceutically acceptable salt thereof and an organic acid； and (b) a second particle part comprising montelukast or a pharmaceutically acceptable salt thereof. The pharmaceutical formulation according to the present invention comprises an organic acid as a stabilizing agent, which can effectively inhibit the production of levocetirizine and montelukast related substances, and thus, show good stability.
