KIM, YONG IL,KIM, DONG HO,KWON, TAEK KWAN,KIM, KYEONG SOO,PARK, JAE HYUN,WOO, JONG SOO
申请号:
EP12814306
公开号:
EP2731594A4
申请日:
2012.07.11
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Disclosed is a capsule formulation for preventing or treating allergic rhinitis and asthma, which comprises two separate layers of: (1) a Montelukast layer comprising montelukast or a pharmaceutically acceptable salt thereof; and (2) a Levocetirizine layer comprising levocetirizine or a pharmaceutically acceptable salt thereof; and a method for the preparation thereof. The capsule formulation according to the present invention can completely separate two active ingredients, thereby minimizing the reactivity between them and improving product stability against aging effects, and thus, can optimize the therapeutic effects.