THOMAS JEFFERSON UNIVERSITY ;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人:
Tykocinski Mark L.
申请号:
US201715803065
公开号:
US2018079821(A1)
申请日:
2017.11.03
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
The present invention provides fusion proteins that act on the glucocorticoid-induced TNFR family-related gene (GITR) and OX40 signaling pathway. The proteins of the invention are useful in modulating both regulatory T (Treg) cells and effector T (Teff) cells.