The United States of America as represented by The Secretary Department of Health and Human Services;KITE PHARMA, INC.
发明人:
Adrian BOT,Jeffrey S. WIEZOREK,William GO,Rajul JAIN,James N. KOCHENDERFER,Steven A. ROSENBERG
申请号：
US15577672
公开号：
US20180344767A1
申请日:
2016.05.27
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes methods of identifying a patient who would respond well to a T cell therapy or conditioning a patient prior to a T cell therapy so that the patient responds well to a T cell therapy. The conditioning involves administering one or more preconditioning agents prior to a T cell therapy and identifying biomarker cytokines prior to administering a T cell therapy.
