LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF

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专利权人:

Jiuzhitang Co., Ltd.

发明人:

ZHAO, Jinhua,WU, Mingyi,GAO, Na,LI, Zi,LAI, Sensen,ZHAO, Longyan

申请号：

EP20130881924

公开号：

EP2985298(A4)

申请日:

2013.12.20

申请国别(地区):

欧洲专利局

年份:

2017

代理人:

摘要：

A low-molecular-weight fucosylated glycosaminoglycan (aTFG) containing 2, 5-anhydrated talose, alditol, glycosylamine or N-substituted glycosylamine monosaccharide composition thereof, preparation method thereof, pharmaceutical compositions containing the aTFG, and use thereof for preventing and/or treating thrombotic diseases are provided. The aTFG has potent anticoagulant activity targeting at intrinsic coagulation factor Xase, and inhibiting thrombogenesis, and therefore can be used as drugs for preventing and/or treating cardiovascular and cerebrovascular diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/