KWON, DAE YOUNG,권대영,SUNG, MI JEONG,성미정,HWANG, JIN TAEK,황진택,PARK, JAE HO,박재호,YANG, HYE JEONG,양혜정,KIM, MYUNG SUNNY,김명선,KIM, HYUN JIN,김현진,HUR, HAEONG JEON,허행전
申请号：
KR1020100065515
公开号：
KR1020120004828A
申请日:
2010.07.07
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A 2,4 D-tertiary-butylphenol or salt thereof for anti-inflammation is provided to suppress iNOS expression and to prevent and treat inflammation.CONSTITUTION: An anti-inflammatory composition contains 2,4 D-tertiary-butylphenol or salt thereof as an active ingredient. A pharmaceutical composition for preventing and treating inflammation contains 2,4 D-tertiary phenol or pharmacologically acceptable salt thereof as an active ingredient. A food composition for preventing and treating inflammation contains 0.01-10 wt% of 2,4-D-tertiary-butylphenol or sitologically acceptable salt thereof as an active ingredient. The salt is acid addition salt.COPYRIGHT KIPO 2012본 발명은 2,4 디-터셔리-부틸페놀 또는 이의 염을 활성성분으로 함유하는 항염증성 조성물을 제공하며, 상기 본 발명에 의하면 염증 유발성 효소인 iNOS의 발현을 억제하고, TNF-α나 인터루킨-6(IL-6)와 같은 친염증성 사이토카인의 분비를 감소시키는 것에 의해 염증의 예방 및 치료에 효과적인 항염증성 조성물로서 제공될 수 있다.
