Wostl, Wolfgang,Jakob-Roetne, Roland,Flohr, Alexander
申请号：
AU2007229550
公开号：
AU2007229550B2
申请日:
2007.03.19
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The invention relates to malonamide derivatives of Formula (I) wherein A is -CHR- or -C(O)-； A is -C(O)- and R/R are independently from each other hydrogen, lower alkyl, halogen, hydroxy or lower alkoxy； or A is -O-C(O)- and R/R are independently from each other hydrogen or lower alkyl； R is hydrogen or lower alkyl substituted by halogen； R is hydrogen, lower alkyl or -(CH)-aryl, optionally substituted by halogen； R is lower alkyl substituted by halogen n is 0, 1 or 2； and to pharmaceutically suitable acid addition salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof for the treatment of Alzheimer's disease.
