MERCK SHARP & DOHME CORP.;Amjad Ali;Michael Man-Chu Lo;Yeon-Hee Lim;Andrew Stamford;Rongze Kuang;Paul Tempest;Younong Yu;Michael Berlin;Pauline Ting;Gang Zhou;Tao Yu;Christopher Boyce;Joseph Michael K
发明人:
Amjad Ali,Michael Man-Chu Lo,Yeon-Hee Lim,Andrew Stamford,Rongze Kuang,Paul Tempest,Younong Yu,Michael Berlin,Pauline Ting,Gang Zhou,Tao Yu,Christopher Boyce,Joseph Michael Kelly,Jayaram R. Tagat,Juny
申请号：
US14655572
公开号：
US09676780B2
申请日:
2013.12.20
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed are compounds of Formula A: (structurally represented) where “RG1”, “RG2a”, “RG4”, “RG5”, “MG1”, “n” and “m” are defined herein which compounds are antagonists of A2A receptor. Disclosed herein also are uses of the compounds described herein as antagonists of the A2a receptor in the potential treatment or prevention of neurological disorders and diseases in which A2A receptors are involved. Disclosed herein also are pharmaceutical compositions comprising these compounds and uses of these pharmaceutical compositions.
