John Dick,Kolja Eppert,Igor Jurisica,Levi David Waldron,Mark Minden,Eric Lechman,Bjorn Nilsson,Benjamin Levine Ebert,Katsuto Takenaka,Jayne S. Danska
申请号：
US13513268
公开号：
US20120237488A1
申请日:
2010.12.03
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A method for determining prognosis in a subject having a hematological cancer comprising: a) determining an expression profile by measuring the gene expression levels of a set of genes selected from a leukemic stem cell (LSC) gene signature marker set or an hematopoietic stem cell (HSC) gene signature marker set, in a sample from a subject and b) classifying the subject as having a good prognosis or a poor prognosis based on the expression profile wherein a good prognosis predicts an increased likelihood of survival within a predetermined period after initial diagnosis and poor prognosis predicts a decreased likelihood of survival within the predetermined period after initial diagnosis.
