BENTLEY, JONATHAN MARK,BROOKINGS, DANIEL CHRISTOPHER,BROWN, JULIEN ALISTAIR,CAIN, THOMAS PAUL,GLEAVE, LAURA JANE,HEIFETZ, ALEXANDER,JACKSON, VICTORIA ELIZABETH,JOHNSTONE, CRAIG,LEIGH, DEBORAH,MADDEN,
申请号：
CA2877543
公开号：
CA2877543A1
申请日:
2013.07.05
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
A series of imidazo[1,2-a]pyrazine derivatives, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorders； and oncological disorders.
