EMORY UNIVERSITY;THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
BONNIE B. PLIKAYTIS,MANI CHERUVU,RAMA ROA AMARA,SURAJ SABLE,THOMAS M. SHINNICK
申请号:
BRPI0905725
公开号:
BRPI0905725A2
申请日:
2009.01.12
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
A vaccine is provided wherein a polypeptide or combination of peptides from M . tuberculosis is administered to a subject to elicit an immune response. The polypeptide vaccine is administered as part of a prime-boost strategy with BCG vaccine to increase the immunoprotection in a subject such that prevention or elimination of disease is achieved. Finally, a pharmaceutical package is provided that encompasses a polypeptide vaccine for M. tuberculosis that when administered to a subject elicits immunoprotection.