Regents of the University of Colorado; a Body Corporate
发明人:
Shapiro Leland,Eli C. Lewis,Charles A. Dinarello
申请号：
US14063986
公开号：
US20140127201A1
申请日:
2013.10.25
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In particular, the present invention relates to compositions and methods for inhibition of graft rejection and promotion of graft survival. Thus, the invention relates to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection and conditions commonly associated with graft rejection. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease and inducers of other alpha1-antitrypsin activities.
