David R Markle,Jeff T Suri,Ritchie A Wessling,Matthew A Romey
申请号：
US12830231
公开号：
US08498682B2
申请日:
2010.07.02
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
