David R. Markle,Jeff T. Suri,Ritchie A. Wessling,Matthew A. Romey
申请号：
US13951125
公开号：
US08983565B2
申请日:
2013.07.25
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
