BLUM, CHARLES A.,BRIELMANN, HARRY,CHENARD, BERTRAND L.,ZHENG, XIAOZHANG
申请号:
CA2577301
公开号:
CA2577301C
申请日:
2005.08.13
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula(I): wherein variables are as described herein. Such compounds are ligandsthat may be used to modulate specific receptor activity in vivo or invitro,and are particularly useful in the treatment of conditions associatedwith pathological receptor activation in humans, domesticated companionanimals and livestock animals. Pharmaceutical compositions and methods forusing such compounds to treat such disorders are provided, as are methods forusing such ligands for receptor localization studies.