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Substituted biaryl piperazinyl-pyridine analogues
专利权人:
Bertrand L. Chenard;Xiaozhang Zheng;Charles A. Blum;Harry Brielmann
发明人:
Charles A. Blum,Harry Brielmann,Bertrand L. Chenard,Xiaozhang Zheng
申请号:
US12705964
公开号:
US08334382B2
申请日:
2010.02.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula:wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
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