Non-Bioconvertible C3-Substituted Pregnenolone Derivatives for Use in the Treatment of Treatment-Resistant Depression

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专利权人:

发明人:

Massimiliano BIANCHI,Etienne BAULIEU,Isabelle VILLEY

申请号：

US15444778

公开号：

US20170252358A1

申请日:

2017.02.28

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to methods for the treatment of treatment-resistant depression (TRD), comprising the administration of compounds of formula (I), which are blocked in C3 position and cannot metabolize in vivo into pregnenolone derivatives and which do not have significant affinity for steroid hormonal receptors and for all tested classical main receptors and receptors of neurotransmitters of the central nervous system.

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中国工程科技知识中心

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