DELUCA, HECTOR F.,FLORES, AGNIESZKA,PLUM, LORI A.,HOLDEN, HAZEL,THODEN, JAMES
申请号:
CA2986694
公开号:
CA2986694A1
申请日:
2016.05.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed are la,25-dihydroxy-24,24-difluoro-2-methylene-19-nor- vitamin D analogs of formula I and their pharmaceutical uses. These new vitamin D analogs are 19-nor-vitamin D analogs having two fluorine atom substitutions at the 24 position (C-24) in the side chain and optionally having a 2-methylene substituent.