Pharmaceutical formulations of N-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide and salts thereof
Greco, Michael Nicholas,Costanzo, Michael John,Green, Michael Alan,Peng, Jirong,Wilde, Victoria Lynn,Zhang, Don
申请号：
AU2018283289
公开号：
AU2018283289A1
申请日:
2018.06.15
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
A pharmaceutical formulation of N-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(l-methyl-lH-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide (compound 1), in particular methanesulfonic acid salt thereof, and methods of using the pharmaceutical formulation for the treatment or prevention of diseases or medical conditions mediated through mutated forms of epidermal growth factor receptor (EGFR), such as various cancers, are disclosed.
