PHARMACEUTICAL SALTS N-(2-(2-(DIMETHYLAMINO)ETHOXY)-4-METHOXY-5-((4-(1-METHYL-1H-INDOL-3-YL)PYRIMIDIN-2-YL)AMINO)PHENYL)ACRYLAMIDE AND CRYSTALLINE FORMS THEREOF
Michael N. Greco,Michael J. Costanzo,Michael A. Green,Jirong Peng,Victoria Lynn Wilde,Don Zhang
申请号：
US16310239
公开号：
US20190233399A1
申请日:
2017.06.16
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Crystalline forms of N-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide (1) and its pharmaceutically acceptable salts and compositions thereof useful for the treatment or prevention of diseases or medical conditions mediated through mutated forms of epidermal growth factor receptor (EGFR), such as various cancers, are disclosed.
